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KMID : 0367419930360030403
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Journal of Korean Pediatric Society
1993 Volume.36 No. 3 p.403 ~ p.408
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Changes of Serum IgG4 in Allergic Patients
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Abstract
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This study was performed to evaluate the changes of serum IgG4 level in children with allergic diseases. Serum Ige, IgG and IgG4 level were measured using enyzme immunoassay (IgE) and radial immunodiffusion method (IgG and IgG4) in 21 children
with
bronchial asthma, allergic rhinitis or urticaria
Eosinophil counts in peripheral blood and the values of serum IgE were significantly increased in allergic patients. The values of IgG4 in allergic patients were also increased compare to those in controls (24.23mg/dl versus 20.33mg/dl). But the
values
of IgG4 were not significantly correlated to either IgG or IgE levels. Further studies will be needed for measuring allergen specifie IgE and IgG4 levels considering the onset of diseases, methods and duration of treatment.
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KEYWORD
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